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Prof. Dr. Rüdiger Klapdor

Chief Physician, Gynecology, Albertinen Hospital
Chief Physician, Obstetrics, Albertinen Hospital

[Translate to English:] Prof. Dr. Rüdiger Klapdor, Chefarzt Klinik für Gynäkologie und Geburtshilfe, Albertinen Krankenhaus, Hamburg-Schnelsen

Practical clinical experience

Since 08/2023 Chief Physician for Gynaecology and Obstetrics at Albertinen Hospital
01/2019 - 08/2023 Senior Physician in Gynaecology and Obstetrics, Hannover Medical School
07/2018 - 04/2021 Functional Senior Physician and Senior Physician of the delivery room
04/2018 – 12/2018 Specialist and Functional Senior Physician for Gynaecology and Obstetrics, Hannover Medical School
06/2018 - 07/2018 Volunteer medical work in Serabu, Sierra Leone, Deutsche Ärzte e.V. project
01/2013 - 04/2018 Assistant Physician in the Department of Gynaecology and Obstetrics, Hannover Medical School
08/2009 - 10/2021 OR Assistant, Die Facharztklinik Hamburg

Other activities

06/2021 - present  Participation in the accreditation process and member of the Study Commission for the midwifery course of study at the Hannover Medical School
Since 10/2020 Education-Management Team CCC-N, Clinical Education coordination, Comprehensive Cancer Center Lower Saxony
06/2018 -present  Obstetrics Quality Management Officer
2018 - present Conducting the first medically supervised birth preparation courses for multiple births in Germany in cooperation with extrakind
12/2003 – 05/2014 Congress Event Management, Hamburg Symposium on Tumour Markers e.V.
01/2003 – 12/2007 Production of patient information films, on behalf of Fresenius Kabi GmbH, ZeTDT GmbH and ADP e.V.

Scientific career

02/2023 - 08/2023 W2-endowed professor of translational gynaecological oncology 
10/2022 Extraordinary professorship at Hannover Medical School
01/2013 - 02/2018 Post-doctoral research and teaching qualification (habilitation) in gynaecology and obstetrics, Title: “Die Sentinellymphonodektomie bei Vulva- und Zervixkarzinom – aktueller Stellenwert und mögliche Optimierung durch den Einsatz des SPECT/CT” (Sentinal lymphadenectomy in vulva and cervical cancer – current status and possible optimization through the use of SPECT/CT)
09/2013 - present Experimental research topic: Adoptive immuntherapy with chimeric antigen receptors (CAR) against gynaecological cancers, in cooperation with Prof. Dr. Dr. Axel Schambach, Institute for Experimental Haematology, Hannover Medical School
08/2010 - 04/2015 Receipt of Doctor of Medicine degree, Title: “Entwicklung von LeGO-Switch-Vektoren, vielseitigen, induzierbaren lentiviralen All-In-One-Vektoren, zur exakten und zuverlässigen Tetracyklin abhängigen Genexpression“ (Development of LeGO switch vectors, versatile, inducible lentiviral all-in-one vectors, for exact and reliable tetracycline gene expression) under the supervision of Prof. Dr. Boris Fehse, Research Department for cell and gene therapy, interdisciplinary clinic and polyclinic for stem cell transplants, University Medical Center Hamburg-Eppendorf (UKE), grade: magna cum laude

Education

04/2020 - 08/2023 Specialist training in gynaecological oncology
08/2020 Certificate in da Vinci robotic surgery
04/2020 Emphasis on special obstetric and perinatal medicine
03/2019 - 04/2023 Parallel course of study for an MBA in health management, University of Hamburg – very good
04/2018 Specialist Physician in gynaecology and obstetrics
10/2006 - 10/2012 University Medical Center Hamburg-Eppendorf (UKE)
Medical studies: 1.3 (final grade)
Physikum (preliminary medical examination): 1.0 (final grade)
Elective "Experimental Oncology": 1.0 (final grade)
Elective "Introduction to Molecular Medicine": 1.0 (final grade)
09/1998 - 07/2006 Johanneum Secondary School, Hamburg
School leaving certificate (abitur): 1.0 (final grade)

Scholarships, grants and scientific awards

10/2022 Lecture prize at the DGGG Congress 2022, "StepOPGyn – A structured training curriculum in operative gynaecology", German Society for Gynaecology and Obstetrics
10/2020 Lecture prize at the DGGG Congress 2020, "SOCIUS Mentoring", German Society for Gynaecology and Obstetrics
10/2020 Poster prize at the DGGG Congress 2020, "Tumor cell dislocation with intracorporal colpotomy", German Society for Gynaecology and Obstetrics
09/2019 Hans Frangenheim Prize of the AGE e.V., Arbeitsgemeinschaft gynäkologische Endoskopie, award: €1500
06/2019 "Beacon of the North (Leuchtfeuer des Nordens)" of the NGGG for the best submitted abstract, Norddeutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V., award: €500
05/2019 AStA-Lehrpreis (for excellence in teaching) of the fourth academic year, Hannover Medical School
09/2017 Staude Pfannenstiel Prize of the NGGG for the best unpublished manuscript, Norddeutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V., award: €2,500
01/2016 - 12/2018 Grant from the Junge Akademie, Clinician Scientist Program of the Hannover Medical School, award: Partial financing of the position and annual award of €5,000
10/2015 - 10/2018 TRAIN Academy, Translational Research & Medicine: "From Idea to Product”, Translational Alliance in Lower Saxony (TRAIN)
10/2016 Lecture prize at the DGGG Congress 2016, "SLN with Vulva-CA, AGO-CaRE-1", German Society for Gynaecology and Obstetrics
10/2016 Poster prize at the DGGG Congress 2016, "Vaginal Sacrocolporectopexy", German Society for Gynaecology and Obstetrics
08/2015 – 08/2016 HILF scholarship, internal university promotion of excellence, Hannover Medical School, award: €18,800
12/2014 Young Teacher Award of the fourth academic year, Hannover Medical School
12/2006 – 12/2012 Scholarship of the German Academic Scholarship Foundation (Studienstiftung des deutschen Volkes e.V.)
06/2006 Bugenhagen Medal, award for the best school leaving certificate (abitur)
06/2006 Johanneum Secondary School, Hamburg
DPG Prize, award for the best accomplishment in physics, German Physical Society
06/2005 Johanneum Secondary School, Hamburg
Deutsche Schülerakademie, Schley

Professional Memberships

1. Publications

1.1. First or last author

1.1.1. Klapdor R, Mücke J, Schneider M, Länger F, Gratz KF, Hillemanns P, Hertel H. Value and advantages of preoperative sentinel lymph node imaging with SPECT/CT in cervical cancer. Int J Gynecol Cancer. 2014 Feb;24(2):295-302. doi:10.1097/IGC.0000000000000032. (IF 1.958)

1.1.2. Mücke J*, Klapdor R*, Schneider M, Länger F, Gratz KF, Hillemanns P, Hertel H. Isthmocervical labelling and SPECT/CT for optimized sentinel detection in endometrial cancer: technique, experience and results. Gynecol Oncol. 2014 Aug;134(2):287-92. doi: 10.1016/j.ygyno.2014.05.001. * shared first author (IF 3,774)

1.1.3. Klapdor R, Länger F, Gratz KF, Hillemanns P, Hertel H. SPECT/CT for SLN dissection in vulvar cancer: Improved SLN detection and dissection by preoperative three-dimensional anatomical localisation. Gynecol Oncol. 2015 Sep;138(3):590-6. doi: 10.1016/j.ygyno.2015.06.011. (IF 4,198)

1.1.4. Hillemanns P, Wimberger P, Reif J, Stepp H, Klapdor R. Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. Lasers Surg Med. 2016 Nov 16. doi: 10.1002/lsm.22613. (IF 2,503)

1.1.5. Klapdor R, Hertel H, Soergel P, Hillemanns P. Groin Recurrences in Node Negative Vulvar Cancer Patients After Sole Sentinel Lymph Node Dissection. Int J Gynecol Cancer 2017 Jan;27(1):166-170. doi: 10.1097/IGC.0000000000000860. (IF 2,192)

1.1.6. Klapdor R, Hillemanns P, Wölber L, Jückstock J, Hilpert F, de Gregorio N, Iborra S, Sehouli J, Habermann A, Fürst ST, Strauß HG, Baumann K, Thiel F, Mustea A, Meier W, Harter P, Wimberger P, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Richter B, Jäger M, Mahner S. Outcome After Sentinel Lymph Node Dissection in Vulvar Cancer: A Subgroup Analysis of the AGO-CaRE-1 Study. Ann Surg Oncol. 2016 Nov 28. (IF 4,200)

1.1.7. Klapdor R, Hertel H, Soergel P, Jentschke M, Hillemanns P. Application of sentinel lymph node dissection in gynecological cancers: results of a survey among German hospitals. Arch Gynecol Obstet. 2016 Dec 29. doi: 10.1007/s00404-016-4279-3. (IF 2,321)

1.1.8. Klapdor R, Grosse J, Hertel B, Hillemanns P, Hertel H. Postoperative anatomic and quality-of-life outcomes after vaginal sacrocolporectopexy for vaginal vault prolapse. Int J Gynaecol Obstet. 2017 Jan 6. doi: 10.1002/ijgo.12095. (IF 1,77)

1.1.9. Klapdor R, Wang S, Hacker U, Büning H, Morgan M, Dörk T, Hillemanns P, Schambach A. Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy. Hum Gene Ther. 2017 Aug 24. doi: 10.1089/hum.2017.168. (IF 4,419)

1.1.10. Klapdor R, Wang S, Morgan M, Dörk T, Hacker U, Hillemanns P, Büning H, Schambach A. Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer. Int J Mol Sci. 2019 Feb 3;20(3). pii: E660. doi:10.3390/ijms20030660 (IF 4,605)

1.1.11. Klapdor R, Wölber L, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Jückstock J, Hilpert F, de Gregorio N, Hillemanns P, Fürst ST, Mahner S. Predictive factors for lymph node metastases in vulvar cancer. An analysis of the AGO-CaRE-1 multicenter study. Gynecol Oncol. 2019 Jun 18. pii: S0090-8258(19)31324-1. doi: 10.1016/j.ygyno.2019.06.013 (IF 4.623)

1.1.12. Klapdor R, Hertel H, Hillemanns P, Röttger M, Soergel P, Kuehnle E, Jentschke M. Peritoneal contamination with ICG-stained cervical secretion as surrogate for potential cervical cancer tumor cell dissemination: A proof-of-principle study for laparoscopic hysterectomy. Acta Obstet Gynecol Scand. 2019 Jun 26. doi:10.1111/aogs.13681 (IF 2,770)

1.1.13. Klapdor, R., Hillemanns, P., Wölber, L., Jückstock, J., Hilpert, F., de Gregorio, N., Hasenburg, A., Sehouli, J., Fürst, S., Strauss, H., Baumann, K., Thiel, F., Mustea, A., Meier, W., Harter, P., Wimberger, P., Hanker, L., Schmalfeld, B., & Mahner, S. (2020). Association between obesity and vulvar cancer recurrence: an analysis of the AGO-CaRE-1 study. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 30(7), 920–926. doi.org/10.1136/ijgc-2019-001187 (IF 3,44)

1.1.14. Röttger, M., Hertel, H., Kaukemüller, L., Brodowski, L., Flentje, M., Hillemanns, P., & Klapdor, R. (2020). Sentinel lymph node biopsy in vulvar cancer: status, level of knowledge, and counseling in outpatient setting. Archives of gynecology and obstetrics, 10.1007/s00404-020-05701-4. Advance online publication. doi.org/10.1007/s00404-020-05701-4 (IF 2,670)

1.1.15. Klapdor R, Weiß C, Kuehnle E, Kohls F, von Ehr J, Philippeit A, Hille-Betz U. Quality of Life after Bilateral and Contralateral Prophylactic Mastectomy with Implant Reconstruction. Breast Care (Basel). 2020 Oct;15(5):519-526. doi: 10.1159/000505449. Epub 2020 Jan 24. PMID: 33223996; PMCID: PMC7650103. (IF 2,860)

1.1.16. Klapdor R, Hertel H, Delebinski L, Hillemanns P. Association of preoperative cone biopsy with recurrences after radical hysterectomy. Arch Gynecol Obstet. 2021 Jul 21. doi: 10.1007/s00404-021-06145-0. Epub ahead of print. PMID: 34291339. (2020 IF 2,670)

1.1.17. Klapdor R, Wang S, Morgan MA, Zimmermann K, Hachenberg J, Büning H, Dörk T, Hillemanns P, Schambach A. NK Cell-Mediated Eradication of Ovarian Cancer Cells with a Novel Chimeric Antigen Receptor Directed against CD44. Biomedicines. 2021 Sep 28;9(10):1339. doi: 10.3390/biomedicines9101339 PMID: 34680456; PMCID: PMC8533227. (IF 6.081)

1.1.18. Fard D, Borchers CS, Philippeit JC, Philippeit AV, Kaukemüller LR, Higgins-Wood LR, Papageorgiou S, Hillemanns P, von Kaisenberg CS, Klapdor R. Comparing forces on the fetal neck in breech delivery in lithotomy versus all-fours position: a simulation model. Arch Gynecol Obstet. 2022 Jul 20. doi: 10.1007/s00404-022-06671-5 Titel anhand dieser DOI in Citavi-Projekt übernehmen. Epub ahead of print. PMID: 35857095

1.1.19. Klapdor R, Kleine M, Schilling T, Huusmann S, Philippeit A, Philippeit J, Timrott K, Kruppa M, Hillemanns P, Imkamp F. SOCIUS Mentoring-A Novel Course to Encourage Students for a Career as Surgical Oncologists. Med Sci (Basel). 2022 Jun 24;10(3):35. doi: 10.3390/medsci10030035

And many additional articles, including articles as co author, reviews and non-listed articles and book chapters.